Piscine Orthoreovirus-1 Isolates Differ in Their Ability to Induce Heart and Skeletal Muscle Inflammation in Atlantic Salmon (Salmo salar)

Piscine orthoreovirus 1 (PRV-1) is the causative agent of Sweater Vests heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon (Salmo salar).The virus is widespread in Atlantic salmon and was present in Norway long before the first description of HSMI in 1999.Furthermore, in Canada the virus is prevalent in farmed Atlantic salmon b

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